Microblogging service Twitter is ever popular, and is a great way for keeping in contact with your friends in real time and seeing what they are up to. What makes Twitter what it is though, is the ability to update your status and receive messages on all sorts of devices, as well as the web interface.
Twitux is a native GTK/Gnome client for Twitter.
It is now apparently in Ubuntu, Fedora and Debian repositories, install it through the package name twitux, or you can download the source here. In my case, I’m installing through the Fedora repositories.
Also: Fosik - A GTK+ front-end to mkisofs