Open-source software may aid brain imaging to find disease treatments
Researchers say the open-source software, called PySight, acts as a photon counting add-on for laser scanning microscopes. Because it can image deep into tissue, a laser-based technique known as multiphoton microscopy is often used to study the rapid activity of neurons, blood vessels and other cells at high resolution over time. The method uses laser pulses that excite fluorescent probes, eliciting the emission of photons, some of which are detected and used to form 2D and 3D images.
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Microscope add-on could be a game-changer for 2D, 3D brain imaging